School of Natural Sciences
Department of Chemistry

Profile of Faculty

Dr. Partha Ghosh

Assistant Professor,
Department of Chemistry,
Central University of Jharkhand, Ranchi

Cell : 9934012120
E-Mail : partha.ghosh@cuj.ac.in

Educational Qualification  
  1. MS from IISc, Bangalore
  2. Ph.D. from Rutgers University, New Brunswick, USA
Awards/ recognition  
  1. Riemann Award for Teaching Excellence (2006)
  2. S. Krishnamurthy Award for Research
Area of Interest   Synthetic Organic Chemistry, Medicinal Chemistry
Courses Taught   Principles of Chemistry, Organic Reaction Mechanism, Organic Spectroscopy, Chemistry of Biomolecules, Medicinal Chemistry, Novel Strategies in Organic Chemistry, Physical Chemistry, Industrial Reactions and Rearrangements, Research Methodology.
Brief Introduction  

Dr.Partha Ghosh obtained his BSc in chemistry from Calcutta University, India and MS in chemical sciences from Indian Institute of Science, Bangalore. He then moved to Rutgers University, USA to pursue PhD under the supervision of Prof. Lawrence. J. Williams. After post-doctoral research with Prof. Jeffrey Aubé at University of Kansas, USA and working as senior scientist at AMRI, Singapore, he joined Central University of Jharkhand, India in 2014 where he is now Assistant Professor. His current research is in the area of developing green synthetic methods with focus on auto-oxidation and cascade reaction.
Administrative responsibilities (with active period)   Assistant Registrar of Academics and Research (October 2020-    )
Additional role/ responsibility  
  1. Departmental Examination in charge (2016-2018)
  2. Departmental Placement in charge (2019-)
Articles Published/Accepted  

Project

  1. Dr. Partha Ghosh (PI) received a research Grant of Rs. 29.18 Lakh from DST-SERB on November 2015 for the project titled “Development of a novel redox neutral transformation of N-heterocycles involving a cascade of reductive arnination, Grab-type fragmentation and Mannich reaction.” Project Reference No. SERB- YSS/2015/000356; Duration 3 years; Status: (Completed).
  2. Dr. Partha Ghosh (PI) received a research Grant of Rs. 6.00 Lakh from UGC on April 2015 as Startup Grant. Project Reference No. F.4-5(108-FRP)/2014, BSR; Duration 3 years; Status: (Completed).

Research publications

Patent

  1. Bolisetti, R.; Cammarano, C. M.; Christopher, M. P.; Fradera, L. F. X; Ghosh, P.; Machacek, M.; Martinez, M.; Panda, J.; Reutershan, M. H.; Samala, J. P.; Shizuka, M.; Sun, B.; Thompson, C. F.; Tony, K. A.; Trotter, B. W.; Voss, M. E.; Yang, L.; Altman, M. D.; Bogen, S. L.; Doll, R. J. Substituted imidazopyridines as hdm2 inhibitors. Application No: PCT/US2013/075906, Publication No. WO2014100065 A1, Application Date: 2013-12-18, Publication Date: 2014-06-26.
  2. 2. Aubé, J.; Roth, B. L.; Ghosh, P.; Frankowski K. J. Preparation of functionalized octahydroisoquinolin-1-one-8-carboxamides, octahydroisoquinolin-1-one-8-carboxylic esters, and analogs as opioid receptor modulators useful in the treatment of diseases. Application No: WO2009US58647, Publication No. WO2010037050, Application Date: 2009- 09-28, Publication Date: 2010-04-01.

Articles in Journals

  1. Sabyasachi Bhunia, Partha Ghosh, Snigdha Rani Patra, 2020. Gold‐Catalyzed Oxidative Alkyne Functionalization by N−O/S− O/C−O Bond Oxidants. Advanced Synthesis & Catalysis. 362 (18): 3664-3708.
  2. Anusueya Kumari, Saurabh Kumar Singh, Raj Bahadur Singh, Sabyasachi Bhunia, Partha Ghosh, 2020. A concise synthesis of 2-benzoyl-1-indanones and 1-indanones from 2-aryl-1-tetralones. Synthetic Communications. 50 (15): 2313-2318.
  3. Partha Ghosh, 2019. Acid-Catalyzed Air-Oxidative Fragmentation of the Carbon−Carbon Bond in 2‑Aryl-1-tetralones. ACS Omega. 4 (5): 8065-8070.
  4. Stephen R Slauson, Ryan Pemberton, Partha Ghosh, Dean J Tantillo, Jeffrey Aube, 2015. Domino Acylation/Diels–Alder Synthesis of N-Alkyl-octahydroisoquinolin-1-one-8-carboxylic Acids under Low-Solvent Conditions. The Journal of organic chemistry. 80 (10): 5260-5271.
  5. Timothy Spicer, Virneliz Fernandez-Vega, Peter Chase, Louis Scampavia, Joyce To, John P Dalton, Fabio L Da Silva, Tina S Skinner-Adams, Donald L Gardiner, Katharine R Trenholme, Christopher L Brown, Partha Ghosh, Patrick Porubsky, Jenna L Wang, David A Whipple, Frank J Schoenen, Peter Hodder, 2014. Identification of Potent and Selective Inhibitors of the Plasmodium falciparum M18 Aspartyl Aminopeptidase (PfM18AAP) of Human Malaria via High-Throughput Screening. Journal of biomolecular screening. 19 (7): 1107-1115.
  6. Kevin J Frankowski, Michael P Hedrick, Palak Gosalia, Kelin Li, Shenghua Shi, David Whipple, Partha Ghosh, Thomas E Prisinzano, Frank J Schoenen, Ying Su, S Vasile, Eduard Sergienko, Wilson Gray, Santosh Hariharan, Loribelle Milan, Susanne Heynen-Genel, Arianna Mangravita-Novo, Michael Vicchiarelli, Layton H Smith, John M Streicher, Marc G Caron, Lawrence S Barak, Laura M Bohn, Thomas DY Chung, Jeffrey Aubé, 2012. Discovery of small molecule kappa opioid receptor agonist and antagonist chemotypes through a HTS and hit refinement strategy. ACS chemical neuroscience. 3 (3): 221-236.
  7. Kai Liu, Hiyun Kim, Partha Ghosh, Novruz G Akhmedov, Lawrence J Williams, 2011. Direct entry to erythronolides via a cyclic bis [allene]. Journal of the American Chemical Society 133 (38): 14968-14971.
  8. Partha Ghosh,  Jeffrey Aubé. Resolution of carboxylic acids using copper (I)-promoted removal of propargylic esters under neutral condition, 2011. The Journal of organic chemistry. 76(10): 4168-4172. 
  9. Kevin J. Frankowski. Partha Ghosh, Setola, Vincent Setola, Thuy B Tran, Bryan L Roth, Jeffrey Aubé.  N-alkyl-octahydroisoquinolin-1-one-8-carboxamides: selective, and nonbasic κopioid receptor ligands, 2010. ACS medicinal chemistry letters. 1 (5): 189-193.
  10.  Partha Ghosh, Weston R Judd, Timothy Ribelin, Jeffrey Aubé. Asymmetric total synthesis of alkaloids 223A and 6-epi-223A, 2009. Organic letters 11 (18): 4140-4142
  11. Partha Ghosh, Joseph R Cusick, Jennifer Inghrim, Lawrence J Williams. Silyl-substituted spirodiepoxides: stereoselective formation and regioselective opening, 2009. Organic letters 11 (20): 4672-4675.
  12. Partha Ghosh, Yue Zhang, Thomas J Emge, Lawrence J Williams. Modeling a bis[spirodiepoxide] strategy to erythronolide A, 2009. Organic letters 11 (19): 4402-4405.
  13. Yue Zhang, Joseph R Cusick, Partha Ghosh, Ning Shangguan, Sreenivas Katukojvala, Jennifer Inghrim, Thomas J Emge, Lawrence J Williams. synthesis of epoxomicinoids, 2009.  The Journal of organic chemistry. 74 (20): 7707-7714.
  14. Partha Ghosh, Stephen D Lotesta, Lawrence J Williams. Spirodiepoxide reaction with cuprates, 2007.  Journal of the American Chemical Society. 129 (9): 2438-2439
  15. Goverdhan Mehta, Partha Ghosh, Katukojvala Sreenivas. Synthetic studies towards pteridanone, a novel protoilludane-type tricyclic sesquiterpenoid. 2003.ARKIVOC. 3: 176-187.

Book Authored:

  1. Partha Ghosh. Novel method and strategies towards erythronolide synthesis, Scholars' Press, Germany, 2014. ISBN: 9783639661798
Seminar/Workshop/Conference/Participation  
  1. Partha Ghosh. Concise green synthesis of CNS drug pregabalin. Oral presentation, International conference on frontiers of chemical sciences, CUJ, Ranchi, March 16-18, 2017.
  2. Partha Ghosh Jeffrey Aubé. Optical resolution of carboxylic acids via copper (I)- catalyzed amination of propargylic ester derivative under mild condition. Poster presentation, 239th ACS National Meeting, San Francisco, CA, United States, March 21-25, 2010.
  3. Partha Ghosh, Lawrence J. Williams. Concise stereocontrolled synthesis of ketoalcohols. Poster presentation, 228th ACS National Meeting, Philadelphia, PA, United States, August 22-26, 2004.
Updated as on  

2021