School of Natural Sciences
Department of Life Sciences

Profile of Faculty

Dr. Praveen Kumar Sharma

Assistant Professor
Department of Life Sciences, Central University of Jharkhand

E-Mail : pksharma@cuj.ac.in
Educational Qualification:  

M.Sc. , Ph.D.
Area of Interest:  
  1. Molecular and Cellular Biology
  2. Neurobiology
  3. Physiology and Biochemistry
Courses Taught:  
  1. Cell Biology (BIO 611010)
  2. Molecular Biology (BIO 621010)
  3. Evolutionary Biology (BIO 711020)
  4. Neurobiology (BIO 726090)
Brief introduction:   Obtained masters and doctoral degree from Department of Zoology, Banaras Hindu University, Varanasi, India and trained in animal molecular biology. My research interest is understanding the role of stressors on the behaviour and cognitive functions. My lab uses Zebra Fish (Danio rerio) as a model organism and behavioural and epigenetic tools. It is known that in response to stress amygdala activates central stress response system known as hypothalamic-pituitary- adrenalcortical (HPA) axis which in turn regulates the stress hormone cortisol. In chronic stress, this system is up all the time and is believed to cause our brains, nervous systems, and behaviour to adjust to a vigilant and reactive state. However the constant vigilance can lead to devastating mental and physical health conditions for the person experiencing it and It can also affect their offspring through epigenetic modifications.
Administrative responsibilities (with active period):  
  1. Member, University Proctorial Board (2012-15, 2017-2020, 2020-cont.)
  2. Administrative Warden (Boy's Hostel; 2011-2013, 2015-2016)
Additional role/ responsibility:  
  1. NSS Coordinator (May 2014- January 2015)
  2. Coordinator, DBT-BUILDER (Nov-2014 to July 2015)
  3. Member, Board of Studies, Department of Life Sciences ( March 2015- March 2017 and July 21-Cont.)
  4. Member, School Board, School of Natural Sciences( Nov 2018-Nov.2020)
  5. Member, University level MOOCs committee (2020-Cont.)
  6. Deaprtmental Co-ordinator Research (From 2018-cont.)
  7. Dy. Nodal Officer CU-CET (2021)
Articles Published/ Accepted:  

Project (Completed/ Ongoing)

  1. A.N Misra (PI), P.K.Sharma (Co-PI), R.K. Mishra (Co-PI), H. Firdaus (Co-PI) and A. Kumar (Co-PI) received a  Grant of Rs. 443.1 Lacs/- from DBT- Govt.of India Nov. 2014- Nov. 2019 Duration 5years; Status: Completed)

Research publications

  1. Mir H, Kapur N, Gales DN,  Sharma PK,  Oprea-Ilies G, Johnson AT, Singh R and Singh S. (2021) CXCR6-CXCL16 Axis Promotes Breast Cancer by Inducing Oncogenic Signaling. Cancers 13, 3568.
  2. Ranjan S. and Sharma PK. (2020) Study of learning and memory in type 2 diabetic model of zebrafish (Danio rerio).Endocrine and Metabolic Science 1(3-4):100058,
  3. Ranjan S. and Sharma PK. (2020) Study of Stress, Anxiety and Depression in Type 2 Diabetic Model of Zebrafish (Danio rerio). Bulletin of Pure & Applied Sciences- Zoology 39A(1):25-35
  4. Ranjan S. and Sharma PK. (2020) Study of BDNF protein expression in type 2 diabetic model of zebrafish (Danio rerio).  Res J Biotechnol 15(3):58-60
  5. Ranjan S. and Sharma PK. (2018) Comprehensiv e In silico Analysis of Single Nucleotide Polymorphism s (SNPs) in Human BDNF Gene. Research & Reviews: A Journal of Life Sciences (8) 128- 139
  6. Ranjan S. and Sharma PK.(2018) Development of High Sugar Induced Hyperglycemia or Type 2 Diabetes in Zebrafish (Danio rerio) Model.  Research & Reviews: A Journal of Health Professions (8) 6-12
  7. Ranjan S. and Sharma PK.(2017) Association of Brain Derived Neurotrophic factor (BDNF) gene SNP G196A with type 2 Diabetes and obesity: A Meta-Analysis Research Journal of Pharmacy and Technology  (10) 4297-4305 ISSN/ISBN No 0974-3618.
  8. Ranjan S. and Sharma PK.(2016)Effect of Environmental Chemical exposures on Epigenetics of Diseases: A Systematic review Int. J. Life. Sci. Scienti. Res., 2016 2 385-403 ISSN/ISBN No 2455-1716
  9. Ranjan S. and Sharma PK.(2016) Effect of Environmental Chemical exposures on Epigenetics of Diseases: A Systematic review Int. J. Life. Sci. Scienti. Res., 2016 2 385-403 ISSN/ISBN No 2455-1716
  10. Gupta P, Sharma PK, Mir H, Singh R, Singh N, Kloecker GH, Lillard JW Jr, Singh S.(2014). CCR9/CCL25 expression in non-small cell lung cancer correlates with aggressive disease and mediates key steps of metastasis. Oncotarget 5( 20) 10170-10179.
  11. Rajesh Singh, Pranav Gupta,Praveen Kumar Sharma,Edwin W. Ades, Susan K. Hollingshead, Shailesh Singh, James W. Lillard Jr. (2014). Prediction and Characterization of helper T cell epitopes from pneumococcal surface adhesin A (PsaA). Immunology 141(4). 514-530. DOI: 10.1111/imm.12194
  12. Christelle P El-Haibi, Praveen Sharma, Rajesh Singh, Pranav Gupta, Dennis D Taub, Shailesh Singh, James W Lillard (2013) Differential G protein subunit expression by prostate cancer cells and their interaction with CXCR5. Molecular Cancer. 12(1):64. DOI:10.1186/1476-4598-12-64
  13. El-Haibi CP, Singh R, Gupta P, Sharma PK, Greenleaf KN, Singh S, Lillard JW Jr. (2012) Antibody microarray analysis of signaling networks regulated by Cxcl13 and Cxcr5 in prostate cancer. J. Proteomics Bioinform.5(8):177-184 doi:10.4172/jpb.1000232
  14. El-Haibi CP, Singh R, Sharma PK, Singh S, Lillard JW Jr. (2011) CXCL13 mediates prostate cancer cell proliferation through JNK signaling and invasion through ERK activation. Cell Prolif. 44(4):311-319
  15. Christelle P El Haibi, Praveen K Sharma, Rajesh Singh, Paul R Johnson, Jill Suttles, Shailesh Singh and James W Lillard Jr. (2010) PI3Kp110-, Src-, FAK- dependent and DOCK2-independent migration and invasion of CXCL13-stimulated prostate cancer Cells. Molecular Cancer, 9:85
  16. Rajesh Singh, Shailesh Singh, Praveen K Sharma, Udai P Singh, David E. Briles, Susan K. Hollingshead, James W. Lillard, Jr (2010) Helper T Cell Epitope- mapping reveals MHC-Peptide binding affinities that correlate with T helper cell responses to Pneumococcal Surface Protein A.  PLos One 5:e9432
  17. Sharma PK, Singh R, Eaton J, Novakovic KR, Chun LWK, Grizzle WE, Singh S (2010). CCR9-CCL25 interaction inhibits drug induced apoptosis of prostate cancer cell. Int. J. Cancer. 127 (9); 2020-2030
  18. Singh S, Singh R, Sharma PK, Singh UP, Rai SN, Chung LWK, Cooper CR, Novakovic KR, Grizzle WE, Lillard JW Jr (2009). Serum CXCL13 positively correlated with prostatic disease, prostate specific antigen and mediates prostate cancer cell invasion, integrin clustering and cell adhesion. Cancer Lett. 283:29-35
  19. Thakur MK, Sharma PK (2008) Binding of Estrogen receptor alpha promoter to nuclear proteins of mouse cerebral cortex; effect of age, sex and gonadal steroids. Biogerontol 9:467-478
  20. Thakur MK, Sharma PK (2007) Transcription of estrogen receptor α and β in mouse cerebral cortex: effect of age, sex, 17 β estradiol and testosterone. Neurochem Int 50:314-321
  21. 21: Sharma PK, Thakur MK (2006) Expression of estrogen receptor (ER) α and β in mouse cerebral cortex: effect of age, sex, and gonadal steroids.  Neurobiol. Aging 27:880-887
  22. Gaur P, Thakur BK, Sharma PK, Oka T, Thakur MK (2005). Expression of perchloric acid soluble 14 kDa protein in mouse brain. Anal. Neurosci. 12: 12-15
  23. Sharma PK, Thakur MK (2004). Estrogen receptor α expression in mice kidney shows sex differences during aging. Biogerontol 5:375-381.
  24. Thakur MK, Sharma PK, Ghosh S, Mani ST (2004). Estrogen intervention in aging and longevity: problems and perspectives. Geriat. Gerontol Int 6: S259-S261.
  25. Thakur MK, Sharma PK (2006). Aging of Brain: Role of Estrogen. Neurochem. Res. 31:1389-1398.

Books and Book Chapters (Published/ Accepted)

Book Chapter

  1. Sharma PK, Rai AK, Sharma NK (2021) Safety and Ethics in Omics Biology. In Omics Technologies for Sustainable Agriculture and Global Food Security Vol.1 (eds. Kumar et al.) Publisher: Springer-Nature, Singapore, Pp 281-297.
  2. Thakur MK, Sharma PK, Ghosh S. (2005) Estrogen effects in the brain: Implications for aging and Alzheimer’s disease. In Molecular and Cellular Neurobiology (eds. MK Thakur and S Prasad), Narosa Publishing House Pvt. Ltd., New Delhi. Pp 55-69.
Seminar/ Workshop/ Conference Participation:  
  1. FDP on MOOCsand Applications of ICT in Academic and Research Libraries (Nov.25-30, 2019) conducted by National Institute of Educational Planning and Administration, New Delhi, India
  2. Resource person: International Brain Research Organization-Asia-Pacific Regional Committee (IBRO-APRC) Shcool of Neuroscience (Advances in molecular neurobiology research) march 3-9 2019 conducted at IGNTU-Amarkantak, M.P. India.
  3. Sharma PK, 2017. Talk delivered in 31st annual conference of Society of neurochemistry India (Advances in research on Aging and Neurological Disorders) organized by CAS in Zoology, Banaras Hindu  University, Varanasi, India during September 20-22, 2017.
  4. Sharma PK, 2017. Chaired a session in 31st annual conference of Society of neurochemistry India (Advances in research on Aging and Neurological Disorders) organized by CAS in Zoology, Banaras Hindu  University, Varanasi, India during September 20-22, 2017.
+ 30 more
Program Organized:  
  1. National Seminar on Challenges and Opertuinities in Life Sciences, 20th April 2018
  2. 2 days MOOCs training program for Faculties of Central University of Jharkhand (Sept 2020)
Lab Members:  
  • Ms. Manisha Pallavi, Doctoral Student
  • Ms. Roseleena  Minz, Doctroal Student
  • Mr. Koushik Mondal, Doctoral Student
Updated as on:   15 Aug. 2021